BeaverBeads™ 二氧化硅系列磁性微球专为核酸提取和纯化设计,表面为二氧化硅材质,修饰大量硅烷醇基团(羟基)或羧基,能在高盐、低pH条件下和溶液中的核酸通过疏水作用、氢键作用和静电作用等发生特异性结合,而不与其他杂质(如蛋白)结合,迅速从生物样品中分离核酸,操作安全简单,非常有利于核酸的自动化和高通量提取。
产品性能
• 核酸结合能力强:>20μgDNA/mg磁珠;
• 操作性能好:磁珠分散均匀,具有超顺磁性,磁响应时间<30s;
• 完整的氧化硅层包覆,使用性能稳定。
应用方向
• PCR产物纯化
• 质粒提取
• 病毒核酸提取
• 血液、组织、植物和微生物等样本中基因组DNA提取
• 磁蛋白纯化
BeaverBeads™ Mag OH-500的TEM成像
引用文献:
1. An SPRI beads-based DNA purifcation strategy for fexibility and cost-efectiveness. BMC Genomics, 2023.
2. Single-walled carbon nanotubes-based RNA protection and extraction improves RT-qPCR sensitivity for SARS-CoV-2 detection. Analytica Chimica Acta, 2023.
3. Mercury bioremediation by engineered Pseudomonas putida KT2440 with adaptationally optimized biosecurity circuit. Environ Microbiol 2022 May 12. DOI: 10.1111/1462-2920.16038.
4. A Rationally Designed Building Block of the Putative Magnetoreceptor MagR. Bioelectromagnetics 2022 Jul;43(5).
5. A magnetic protein biocompass;NATURE MATERIALS 卷: 15 期: 2 页: 217-226 出版年: FEB 2016
6. Novel Application of Magnetic Protein: Convenient One-Step Purification and Immobilization of Proteins;SCIENTIFIC REPORTS , 7,13329; DOI:10.1038/s41598-017-13648-x